TABLE 3.

Creatinine, urea, iohexol, cystatin C, and vancomycin (total and free) clearances together with plasma concentrations of creatinine, urea, and cystatin C and excretion of creatinine and urea during the 6 days of clearance studies.

Vancomycin study day	1	2	3	4	5	6
Day from start of symptoms	9	10	11	12	13	14
Plasma creatinine (µmol/L)	46	44	44	59	51	43
Creatinine clearance (ml/min)	-	305	272	170	139	294
Creatinine clearance (mL/min/1.73 m2)	-	214	190	119	97	206
Urine excretion of creatinine, mmol/24 h		19.2	17.2	14.2	10.2	18.2
Plasma urea (mmol/L)		2.1	2.6	3.5	2.5	2.4
Urea clearance (ml/min)		179	119	71	71	111
Urea clearance (mL/min/1.73 m2)		125	84	50	50	78
Urine excretion of urea, mmol/24 h		536	447	360	256	384
Iohexol clearance, mL/min	177 a	-	-	-	-	189
Iohexol clearance (mL/min/1.73 m2)	119 a	-	-	-	-	129
Plasma cystatin C (mg/L)	-	0.79	0.61	0.79	0.64	0.7
Cystatin C clearance (ml/min)	-	154	206	153	195	174
Cystatin C clearance (mL/min/1.73 m2)	-	104	139	104	132	119
Vancomycin clearance (ml/min)	190	-	237	-	-	199
Vancomycin clearance (mL/min/1.73 m2)	128	-	160	-	-	136
Free vancomycin clearance (ml/min)	251	-	281	-	-	254
Free vancomycin clearance (mL/min/1.73 m2)	169	-	190	-	-	174

^aCalculated from iohexol given at the Department of Radiology.