Table 3.
Laboratory characteristics of 118 SARS-CoV-2 positive patients at admission by liver function tests
| Parameter | Total | Patients with normal LFTs (n = 66) | Patients with LFT abnormalities (n = 52) | P-value |
|---|---|---|---|---|
| WBCs (109/l), median (IQR) | 6.8 (4.58-8.92) | 6.95 (4.35-9.1) | 6.7 (5-8.9) | 0.73 |
| Lymphocytes (109/l), median (IQR) | 1.2 (1.55-2.52) | 1.47 (1.25-2.39) | 1.8 (1.03-2.7) | 0.56 |
| Hemoglobin (g/dl), median (IQR) | 12.35 (10.8-13.52) | 11.7 (10.77-13.1) | 12.75 (11-14.1) | 0.04 |
| Platelets (109/l), median (IQR) | 230 (188-280) | 239 (191-308) | 216 (180-259) | 0.12 |
| ALT (U/l), median (IQR) | 30.5 (20-45.75) | 22.5 (17-30.25) | 50.5 (37-67) | 0.000 |
| AST (U/l), median (IQR) | 32 (21.75-44.25) | 23 (16.75-32) | 47.5 (39-64.5) | 0.000 |
| Albumin (g/dl), median (IQR) | 3.95 (3.67-4.32) | 4 (3.8-4.5) | 3.75 (3.4-4.17) | 0.001 |
| Total bilirubin (mg/dl), median (IQR) | 0.6 (0.43-0.77) | 0.53 (0.41-0.65) | 0.7 (0.55-0.81) | 0.000 |
| INR, median (IQR) | 0.91 (0.78-0.91) | 0.9 (0.73-1) | 0.92 (0.73-1.1) | 0.58 |
| CRP (mg/dl), median (IQR) | 6 (12-24) | 9.5 (6-21) | 12 (10-48) | 0.011 |
| ESR (mm), median (IQR) | 46 (20-83.5) | 39 (17.25-70) | 65.5 (27.25-96.5) | 0.015 |
| Ferritin (ng/ml), median (IQR), | 187 (85-326) | 121 (72.75-282) | 300 (165-365) | 0.000 |
| D-dimer (ng/ml), median (IQR) | 348 (150-562) | 275 (150-501) | 425 (168-700) | 0.03 |
| Glucose (mg/dl), median (IQR) | 134.9 (98.75-178.2) | 115 (95-157) | 156 (105-195) | 0.007 |
| Creatinine (mg/dl), median (IQR) | 1 (0.8-1.3) | 1 (0.8-1.3) | 1 (0.72-1.3) | 0.37 |
| Urea (mg/dl), median (IQR) | 29 (21-42) | 30.5 (21.75-41.55) | 29 (20.25-42.75) | 0.45 |
LFT – liver function test, IQR – interquartile range, ALT – alanine aminotransferase, AST – aspartate aminotransferase, INR – international normalized ratio, CRP – C-reactive protein, ESR – erythrocyte sedimentation rate