Garland 2019.

Study characteristics
Methods	Study design: randomized controlled trial Study grouping: parallel group
Participants	Substance: opioids Baseline characteristics Mindfulness‐based intervention Number randomized: 15 Control 1 Number randomized: 15 Overall Number randomized: 30 Included criteria: 18 years or older, admitted to MMT in the past year, chronic non‐cancer pain, English speaking Excluded criteria: none Number missing: 0 Reason missing: n/a Baseline differences: not reported Age: 50.4 Percent female: 50% Race/Ethnicity: 53% African American, 36.7% White, 20% Hispanic
Interventions	Intervention characteristics Mindfulness‐based intervention Group name: Mindfulness‐oriented recovery enhancement Theory: MORE (Garland, 2013) Duration: 8 weeks Timing: 1x week 2hours Delivery: group Providers: masters‐level clinician Co‐intervention: Methadone maintenance therapy Integrity: supervised by first author / developer of MORE, recordings reviewed during weekly supervision Compliance: not reported Control 1 Group name: TAU Theory: process‐oriented, present‐centered therapy and cognitive behavioral coping skills training Duration: 8 weeks Timing: not reported Delivery: not reported Providers: not reported Co‐intervention: methadone maintenance therapy Integrity: not reported Compliance: not reported
Outcomes	Treatment acceptability (attrition) Outcome type: dichotomous outcome Reporting: fully reported Direction: lower is better Data value: endpoint Time point: post‐treatment
Identification	Sponsorship source: NCCAM, NIDA Country: USA Setting: not residential Authors name: Eric L. Garland Institution: University of Utah Email: eric.garland@socwk.utah.edu Address: College of Social Work and Center on Mindfulness and Integrative Health Intervention Development, University of Utah, 395 South, 1500 East, Salt Lake City, UT 84112 USA COI: Eric Garland, PhD, LCSW is the Director of the Center on Mindfulness and Integrative Health Intervention Development. The Center provides Mindfulness‐Oriented Recovery Enhancement (MORE), mindfulness‐based therapy, and cognitive behavioral therapy in the context of research trials for no cost to research participants; however, Dr. Garland has received honoraria and payment for delivering seminars, lectures, and teaching engagements (related to training clinicians in MORE and mindfulness) sponsored by institutions of higher education, government agencies, academic teaching hospitals, and medical centers. Dr. Garland also receives royalties from the sale of books related to MORE. Diagnosis tool: receiving methadone maintenance therapy Diagnosis type: informal Funding: NCCAM, NIDA Journal: Drug and Alcohol Dependence Publication type: published report Secondary publications: none
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Judgement comment: not reported
Allocation concealment (selection bias)	Unclear risk	Judgement comment: not reported
Blinding of participants and personnel (performance bias) All outcomes	High risk	Judgement comment: no blinding
Blinding of outcome assessment (detection bias) Treatment acceptability (attrition)	Low risk	Objective measure
Incomplete outcome data (attrition bias) All outcomes	Low risk	Judgement comment: similar attrition across groups and not lost to follow‐up
Selective reporting (reporting bias)	High risk	Judgement comment: protocol available and not all outcomes reported
Other bias: equivalence of baseline characteristics (selection bias)	Low risk	Judgement comment: no baseline differences