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. 2021 Sep 20;13(9):e18115. doi: 10.7759/cureus.18115

Table 1. Comparison of risk factors between both groups.

BMI: body mass index, CKD: chronic kidney disease, H2RA: histamine–2 receptor antagonists, PPI: proton pump inhibitor

Risk factors Case group (n=200) Control group (n=200) Odds ratio p-value
Age greater than 65 31 (15.5%) 16 (8.0%) 2.10 (1.11-3.99) 0.02
Male 98 (49.0%) 100 (50.0%) 1.04 (0.70-1.54) 0.84
Hospitalization in last 30 days 51 (25.5%) 12 (6.0%)  5.36 (2.75-10.42) <0.0001
Antibiotics in last 30 days 72 (36.0%) 21 (10.5%) 4.76 (2.80-8.19) <0.0001
PPIs in last 30 days 46 (23.0%) 21 (10.5%) 2.54 (1.45-4.45) 0.001
H2RA in last 30 days 32 (16.0%) 20 (10.0%) 1.71 (-.94-3.11) 0.07
BMI more than 25 kg/m2 62 (31.0%) 42 (21.0%) 1.69 (1.07-2.65) 0.02
Diabetes 54 (27.0%) 32 (16.0%) 1.94 (1.18-3.17) 0.008
Hypertension 31 (15.5%) 29 (14.5%) 1.08 (0.62-1.87) 0.77
CKD 38 (19.0%) 19 (9.5%) 2.23 (1.23-4.03) 0.007
Malignancy 12 (6.0%) 4 (2.0%) 3.12 (0.99 to 9.86) 0.05
Hypercholesterolemia 22 (11.0%) 20 (10.0%) 1.08 (0.57-2.06) 0.79