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. 2021 Oct 20;29(1):5–18.e6. doi: 10.1016/j.chembiol.2021.10.008

Figure 3.

Figure 3

Proximity labeling map of SARS-CoV-2

(A) The 1,388 identified high-confidence human proximal proteins (blue circle nodes) for the SARS-CoV-2 proteins (red diamond nodes). The thickness of the edges is proportional to the ratio values of biotinylated sites in the sample and control.

(B–E) The proximal proteins were mapped to altered proteins of the transcriptome (B), proteome (C), phosphoproteome (D) and ubiquitinome (E). Red circle nodes, upregulated proteins; blue circle nodes, downregulated proteins; green circle nodes, dynamically regulated proteins; gray diamond nodes, viral proteins.