Fig. 2.

IgG1 decline is more discriminative than IgG in paired pre- and post-treatment sera for patients that completed treatment (group A). In each panel (a–d), ELISA absorbance values are shown connected for individual sample pairs, and in the insets as composite box and whisker plots, blue (pre-treatment) and red (post-treatment). a IgG1 with lysate (P < 0.0001 for pre- versus post-treatment); b IgG with lysate (P < 0.0001); c IgG1 with TSSApep-II/V/VI (P < 0.0001); d IgG with TSSApep-II/V/V (P < 0.0001). The dashed line represents each assay cut-off value