Table 1.
Patients' demographic and clinical characteristics stratified according to serum 25-OH vitamin D levels
| Variables | Study population N (%) or mean (± SD) (n = 104) | 25-OH Vit D < 20 ng/ml N (%) or mean (± SD) (n = 74) | 25-OH Vit D ≥ 20 ng/ml N (%) or mean (± SD) (n = 30) | p value |
|---|---|---|---|---|
| Age (years) | 62.71 (± 12.41) | 63.28 (± 11.76) | 61.30 (± 14.01) | 0.463 |
| Gender: | 0.516 | |||
| Female | 40 (38.5%) | 27 (36.5%) | 13 (43.4%) | |
| Male | 64 (61.5%) | 47 (63.5%) | 17 (56.7%) | |
| ASA scores: | 0.043* | |||
| 1 | 17 (16.3%) | 8 (10.8%) | 9 (30%) | |
| 2 | 56 (53.8%) | 41 (55.4%) | 15 (50%) | |
| 3 | 31 (29.8%) | 25 (33.8%) | 6 (20%) | |
| NRS scores: | 0.106 | |||
| 0 | 58 (55.8%) | 38 (51.4%) | 20 (66.7%) | |
| 1 | 31 (29.8%) | 22 (29.7%) | 9 (30%) | |
| 2 | 15 (14.4%) | 14 (18.9%) | 1 (3.3%) | |
| CEA (µg/l) | 7.4 (± 11.6) | 7.44 (± 12.94) | 6.56 (± 6.76) | 0.758 |
| Albumin (gr/dl) | 3.8 (± 0.5) | 3.88 (± 0.51) | 3.87 (± 0.49) | 0.832 |
| Hemoglobin (gr/l) | 12.6 (± 1.99) | 12.11 (± 2.0) | 12.26 (± 1.98) | 0.714 |
| WBC (103/µl) | 8080 (± 2274) | 8340 (± 2479) | 7440 (± 1517) | 0.169 |
| Tumor location: | 51 (68.9%) | 23 (76.7%) | 0.011* | |
| Colon | 74 (71.1%) | 23 (31.1%) | 7 (23.3%) | |
| Rectum | 30 (28.8%) | |||
| Operative procedures: | 0.325 | |||
| Right hemicolectomy | 20 (19.2%) | 16 (21.6%) | 4 (13.3%) | |
| Extended right hemicolectomy | 5 (4.8%) | 5 (6.8%) | – | |
| Left hemicolectomy | 6 (5.8%) | 5 (6.8%) | 1 (3.3%) | |
| Extended left hemicolectomy | 8 (7.7%) | 5 (6.8%) | 3 (10%) | |
| Anterior resection | 14 (13.5%) | 9 (12.2%) | 5 (16.7%) | |
| Low anterior resection | 39 (37.5%) | 24 (32.4%) | 15 (50%) | |
| Abdominoperineal resection | 6 (5.8%) | 6 (8.1%) | – | |
| Total colectomy | 6 (5.8%) | 4 (5.4%) | 2 (6.7%) | |
| pTNM staging: | 0.036* | |||
| I | 19 (18.3%) | 16 (21.6%) | 3 (10%) | |
| IIa | 35 (33.7%) | 23 (31.1%) | 12 (40%) | |
| IIb | 9 (8.7%) | 8 (10.8%) | 1 (3.3%) | |
| IIc | 1 (1%) | – | 1 (3.3%) | |
| IIIa | 5 (4.8%) | 3 (4.1%) | 2 (6.7%) | |
| IIIb | 26 (25%) | 21 (28.4%) | 5 (16.7%) | |
| IIIc | 7 (6.7%) | 2 (2.7%) | 5 (16.7%) | |
| IVc | 1 (1%) | – | 1 (3.3%) | |
| Pathological grading: | 0.693 | |||
| G1 (well differentiated) | 22 (21.8%) | 17 (23.6%) | 5 (17.2%) | |
| G2 (moderately differentiated) | 74 73.3%) | 52 (72.2%) | 22 (75.9%) | |
| G3 (poorly differentiated) | 5 (5%) | 3 (4.2%) | 2 (6.9%) |
SD, standard deviation; ASA, American Society of Anesthesiologists; NRS, Nutritional Risk Score-2002; CEA, carcinoembryonic antigen; WBC, White blood cells; pTNM, pathological tumor-node-metastasis
* Variables with p value < 0.05