Table 5.
Clinical trials on the role of probiotics in treating H. pylori infections (https://clinicaltrials.gov/)
| Row | Identifier | Start year | Participants | Allocation | Intervention model | Masking | Primary Purpose | Status | Country |
|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT04319991 | 2019 | 100 | Randomized | Parallel assignment | Single (Participant) | Supportive Care | Recruiting | Taiwan |
| 2 | NCT01115296 | 2010 | 100 | Randomized | Parallel assignment | Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor) | Treatment | Unknown | Italy |
| 3 | NCT03150394 | 2017 | 80 | Randomized | Parallel assignment | Double (Participant, Investigator) | Treatment | Unknown | Spain |
| 4 | NCT04178187 | 2019 | 800 | Randomized | Parallel assignment | Single (Participant) | Treatment | Recruiting | Greece |
| 5 | NCT01969331 | 2008 | 804 | Randomized | Parallel assignment | Triple (Participant, Care Provider, Investigator) | Treatment | Completed | Croatia |
| 6 | NCT02645201 | 2016 | 0 | Randomized | Parallel assignment | Triple (Participant, Care Provider, Investigator) | Treatment | Withdrawn | Belgium, Croatia, Germany, Israel, Slovenia |
| 7 | NCT03220542 | 2016 | 360 | Randomized | Factorial assignment | Single (Participant) | Treatment | Unknown | Korea |
| 8 | NCT03722433 | 2018 | 200 | Randomized | Parallel assignment | Double (Participant, Care Provider) | Treatment | Unknown | Taiwan |
| 9 | NCT03997279 | 2019 | 200 | Randomized | Parallel assignment | Triple (Participant, Care Provider, Investigator) | Treatment | Unknown | Sebria |
| 10 | NCT03377933 | 2019 | 40 | N/A | Single group assignment | None (Open Label) | Treatment | Unknown | China |
| 11 | NCT04473079 | 2020 | 100 | Randomized | Parallel assignment | Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor) | Supportive Care | Recruiting | Thailand |
| 12 | NCT04527055 | 2020 | 252 | Randomized | Parallel Assignment | Single (Outcomes Assessor) | Treatment | Enrolling by invitation | Taiwan |
| 13 | NCT03297242 | 2017 | 30 | N/A | N/A | N/A | N/A | Unknown | China |
| 14 | NCT04786938 | 2016 | 63 | Randomized | Parallel assignment | Single (Participant) | Treatment | Completed | Ecuador |
| 15 | NCT02689583 | 2016 | 3000 | Randomized | Parallel assignment | Single (Participant) | Treatment | Unknown | China |
| 16 | NCT03688828 | 2018 | 776 | Randomized | Parallel assignment | Triple (Participant, Investigator, Outcomes Assessor) | Treatment | Recruiting | China |
| 17 | NCT03404440 | 2016 | 56 | Randomized | Parallel assignment | Double (Participant, Investigator) | Treatment | Completed | Italy |
| 18 | NCT01456728 | 2011 | 56 | Randomized | Parallel assignment | Double (Participant, Investigator) | Treatment | Completed | Bulgaria |
| 19 | NCT02051348 | 2014 | 24 | Non-Randomized | Crossover assignment | Single (Participant) | Treatment | Completed | Ireland |