Figure 4.

α-syn activated microglia are rescued from their inflammatory program by naive microglia

(A) Heatmap of Pearson Correlation ρ value for the means of gene expression values in acceptors and donors over 5 h of co-culture.

(B) 2D PCA and (C) heatmap of 78 DE genes in donors between 0 and 300 min of co-culture.

(D) Heatmap for top 15 enriched GO terms sorted according to the Enrichment Scores (ES) in donors at 0 min up to 300 min of co-culture with acceptors.

(E) Bar chart of ES for selected GO terms in donors and acceptors at 0 and 300 min.

(F) ES for selected GO terms in donors’ transcriptomes over time in co-culture with acceptors. Green line indicates the baseline ES at 0 min.

See also Figures S3 and S4.