Supplementary Figure 7.

Fecal BA levels of BF⁺ and BF^– patients with IBS. (A) Levels of primary BAs in stool samples of BF⁺ (orange) and BF^– (blue) patients with IBS. (B) Levels of secondary BA in stool samples of BF⁺ and BF^– patients with IBS. (C) Levels of tauro- and glycol-conjugated BA in stool samples of BF⁺ and BF^– patients with IBS. (D) Correlation of colonic R. gnavus OTU relative abundance and fecal BA levels. (A–C) Mann Whitney U test with Bonferroni correction for multiple comparisons. (D) Pearson correlation of centered log-ratio transformed OTU abundance and fecal BA levels. (A–C) n = 14 BF⁺, n = 14 BF^–, (D) n = 40.