The multivariable Cox proportional hazards regression models for assessing the effect modification of tumor differentiation according to tumor size for early recurrence (within 2 years after surgery) of Por differentiated HCC (n = 286) and W-M differentiated HCC (n = 821). Each HR and its 95% CI of poor differentiation for tumors measuring 2 and 5 cm. Por, poorly differentiated; W-M, well- or moderately; HCC, hepatocellular carcinoma; HRs, hazard ratios; CI, confidence interval; OS, overall survival; RFS, recurrence-free survival.