Table 1.
Variants with >85% AI and eQTL PICS probabilities
| Gene symbol | GWAS autoimmune disease category | GTEx tissue type | RSID | AI disease PICS probability | eQTL PICS probability |
|---|---|---|---|---|---|
| CCL20 | Inflammatory bowel disease | Thyroid | rs1811711 | 1 | 1 |
| CCL20 | Ulcerative colitis | Thyroid | rs1811711 | 1 | 1 |
| TRAF3IP2-AS1 | Psoriasis | Transformed fibroblasts | rs33980500 | 0.9999 | 0.9797 |
| TRAF3IP2-AS1 | Psoriasis | Unexposed skin | rs33980500 | 0.9999 | 0.9797 |
| TRAF3IP2-AS1 | Psoriasis | Thyroid | rs33980500 | 0.9999 | 0.9797 |
| TRAF3IP2-AS1 | Psoriasis | Whole blood | rs33980500 | 0.9999 | 0.9797 |
| UBASH3A | Primary sclerosing cholangitis | Transverse colon | rs1893592 | 0.9992 | 0.8706 |
| UBASH3A | Primary sclerosing cholangitis | Lung | rs1893592 | 0.9992 | 0.9494 |
| UBASH3A | Primary sclerosing cholangitis | Thyroid | rs1893592 | 0.9992 | 0.9494 |
| UBASH3A | Primary sclerosing cholangitis | Whole blood | rs1893592 | 0.9992 | 0.9494 |
| UBASH3A | Rheumatoid arthritis | Transverse colon | rs1893592 | 0.9989 | 0.8706 |
| UBASH3A | Rheumatoid arthritis | Lung | rs1893592 | 0.9989 | 0.9494 |
| UBASH3A | Rheumatoid arthritis | Thyroid | rs1893592 | 0.9989 | 0.9494 |
| UBASH3A | Rheumatoid arthritis | Whole blood | rs1893592 | 0.9989 | 0.9494 |
| UBASH3A | Celiac disease | Transverse colon | rs1893592 | 0.9958 | 0.8706 |
| UBASH3A | Celiac disease | Lung | rs1893592 | 0.9958 | 0.9494 |
| UBASH3A | Celiac disease | Thyroid | rs1893592 | 0.9958 | 0.9494 |
| UBASH3A | Celiac disease | Whole blood | rs1893592 | 0.9958 | 0.9494 |
| UBASH3A | Autoimmunitya | Transverse colon | rs1893592 | 0.995 | 0.8706 |
| UBASH3A | Autoimmunitya | Lung | rs1893592 | 0.995 | 0.9494 |
| UBASH3A | Autoimmunitya | Thyroid | rs1893592 | 0.995 | 0.9494 |
| UBASH3A | Autoimmunitya | Whole blood | rs1893592 | 0.995 | 0.9494 |
| OVOL1 | Allergy | EBV-transformed lymphocytes | rs10791824 | 0.9987 | 0.8908 |
| JAZF1 | Systemic lupus erythematosus | Pancreas | rs10245867 | 0.9967 | 0.9765 |
| IRF4 | Vitiligo | Lung | rs12203592 | 0.9957 | 0.9479 |
| IRF4 | Vitiligo | Whole blood | rs12203592 | 0.9957 | 0.9401 |
| IL27 | Type 1 diabetes | Whole blood | rs151234 | 0.9823 | 0.9039 |
| EVI5 | Systemic lupus erythematosus | Thyroid | rs6662618 | 0.9676 | 0.8856 |
| EIF3C | Juvenile idiopathic arthritis | Pancreas | rs12928404 | 0.9648 | 0.8839 |
| TUFM | Juvenile idiopathic arthritis | Transformed fibroblasts | rs12928404 | 0.9648 | 0.9104 |
| RTEL1 | Juvenile idiopathic arthritis | Whole blood | rs2738774 | 0.9509 | 0.8931 |
a
Multiple autoimmune diseases in a single study.