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Fig. 2. Effect of REEs on bioelectrocatalytic performance of NAD+-dependent GDH. (a) Amperometric current responses of the GDH-based biosensor toward titrations of 10 and 20 μM glutamate at 0.0 V vs. Ag/AgCl in aCSF containing 2 mM NAD+ in the absence or presence of 16 μM Yb3+, La3+ or Eu3+. (b) Relative sensitivity of the GDH-based glutamate biosensor.