Fig. 5. Protein conformation of GDH. (a) Scattering intensities of GDH in aCSF containing NAD⁺ in the absence (black) and presence (red) of Yb³⁺ by SAXS. (b) Corresponding pair distances distribution function obtained from (a). (c) R_g encoding protein size information calculated from (b). Error bars represent standard error of the mean (n = 8, t-test, ***P < 0.001). (d) Schematic illustration of Yb³⁺-induced GDH conformation change into a more compact state.