Table 1.
Overview of the direct approaches to assess taste loss in participants.
| Taste Quality Measured | ||||||||
|---|---|---|---|---|---|---|---|---|
| Test | Article | Test Method | Test Objective | Salty | Sweet | Sour | Bitter | Umami |
| Four-solution test |
Vaira et al., 2020a–2020f Petrocelli et al., 2020A |
1 mL of each solution, plus deionized water as control, placed on the participant’s tongue via cotton swab. Quarantined patients prepared their own solutions. | Identification | ☑ | ☑ | ☑ | ☑ | ⨆ |
| Four-solution test & Taste Strips |
Altin et al., 2020
Salcan et al., 2021 |
Participants swallowed and identified the solution. Next, paper strips dipped into each solution and placed on the participant’s tongue. | Identification Duration | ☑ | ☑ | ☑ | ☑ | ☑ |
| Two-solution test (1) | Bidkar et al., 2020 | Two drops (2 mL) of each solution placed on the participant’s tongue via pipette. | Identification | ☑ | ☑ | ⨆ | ⨆ | ⨆ |
| Two-solution test (2) | Mazzatenta et al., 2020 | 200 μl of each solution dropped onto participant’s tongue. | Detection | ☑ | ☑ | ⨆ | ⨆ | ☑ |
| Taste Strips by BMGB | Hintschich et al., 2020 Singer-Cornelius et al., 2021 Le Bon et al., 2021 Niklassen et al., 2021C |
Taste strips (provided by Burghart Messtechnik GmbH) placed on the participant’s tongue. | Identification and threshold concentration | ☑ | ☑ | ☑ | ☑ | ⨅ |
| Taste sprays | Niklassen et al., 2021C | Each solution sprayed onto participant’s tongue. | Identification | ☑ | ☑ | ☑ | ☑ | ⨆ |
| Tastant capsules | Adamczyk et al., 2020 | Each of ten 0.33 mL gelatin capsules (one tasteless and nine with tastant) dissolved on participant’s tongue. | Description | ☑ | ☑ | ☑ | ☑ | ⨆ |
| Brief Self-Administered Waterless Empirical Taste Test (SA-WETT)B | Cao et al., 2021 | 27 disposable plastic strips that contain dried solutions of each taste (and some tasteless strips) self-placed on participant’s tongue. | Identification | ☑ | ☑ | ☑ | ☑ | ☑ |
| Chemosensory Test by India Protocol | Ramteke et al., 2020 | Authors used coconut oil, chocolates, and flavored milk to test smell and taste function. No further details are provided. | N/A | N/A | ||||
These studies used a sweet solution concentration that is double what was used in the other four-solution tests.
Validated test.
Niklassen et al. (2021) used both Taste Strips and taste sprays with participants.