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[Preprint]. 2021 Oct 9:2021.10.09.21264771. [Version 1] doi: 10.1101/2021.10.09.21264771

Table 1.

Overview of the direct approaches to assess taste loss in participants.

Taste Quality Measured
Test Article Test Method Test Objective Salty Sweet Sour Bitter Umami
Four-solution test Vaira et al., 2020a2020f
Petrocelli et al., 2020A
1 mL of each solution, plus deionized water as control, placed on the participant’s tongue via cotton swab. Quarantined patients prepared their own solutions. Identification
Four-solution test & Taste Strips Altin et al., 2020
Salcan et al., 2021
Participants swallowed and identified the solution. Next, paper strips dipped into each solution and placed on the participant’s tongue. Identification Duration
Two-solution test (1) Bidkar et al., 2020 Two drops (2 mL) of each solution placed on the participant’s tongue via pipette. Identification
Two-solution test (2) Mazzatenta et al., 2020 200 μl of each solution dropped onto participant’s tongue. Detection
Taste Strips by BMGB Hintschich et al., 2020
Singer-Cornelius et al., 2021
Le Bon et al., 2021
Niklassen et al., 2021C
Taste strips (provided by Burghart Messtechnik GmbH) placed on the participant’s tongue. Identification and threshold concentration
Taste sprays Niklassen et al., 2021C Each solution sprayed onto participant’s tongue. Identification
Tastant capsules Adamczyk et al., 2020 Each of ten 0.33 mL gelatin capsules (one tasteless and nine with tastant) dissolved on participant’s tongue. Description
Brief Self-Administered Waterless Empirical Taste Test (SA-WETT)B Cao et al., 2021 27 disposable plastic strips that contain dried solutions of each taste (and some tasteless strips) self-placed on participant’s tongue. Identification
Chemosensory Test by India Protocol Ramteke et al., 2020 Authors used coconut oil, chocolates, and flavored milk to test smell and taste function. No further details are provided. N/A N/A
A

These studies used a sweet solution concentration that is double what was used in the other four-solution tests.

B

Validated test.

C

Niklassen et al. (2021) used both Taste Strips and taste sprays with participants.