FIG 3.
Anti-EEHV3 maternal antibody levels over time in African elephant calves that experienced lethal EEHV-HD. (A) Anti-EEHV antibody levels from birth until the date of death from EEHV-HD for elephant IDZ-1. The specific EEHV antigen tested is indicated to the left of the graphs. The black bar in each graph represents antibody levels detected in the dam on the day of parturition. The striped horizontal bar above the graphs indicates the start date and duration of clinical illness, as well as the date of death (DOD). Antibody levels are expressed in RLUs and plotted on a log10 scale. The dashed lines indicate the cutoff levels for determining the sensitivity and specificity for each viral antigen, which were derived from the mean antibody titers of seronegative serum samples or no-serum controls plus 5 SDs. (B) Same as described for panel A for elephant IDZ-2.