Fig. 6. Macromolecular synthesis (MMS) inhibition for the mode of action for compound 25. CIP (ciprofloxacin), RIF (rifampicin), CER (cerulenin) and LNZ (linezolid) are the positive controls for DNA synthesis, RNA synthesis, lipid synthesis, and protein synthesis respectively. All the positive controls were tested at 8xMIC and compound 25 was tested in the range of 0.25× to 1× MIC.