Fig. 3. Comparison of molecular properties for this compound collection (blue) and a commercially available epigenetic compound collection (grey). A: Molecular weight vs. A Log P. B: Principal moment of inertia plot. The commercially available epigenetic library is shown in grey and our focused library described is shown in blue. A Log P and principal moment of inertia (PMI) were calculated in RDKit. PMI represents the three-dimensional shape of a molecule where rod-like molecules are in the top left, disc-like molecules are at the lower middle, and sphere-like molecules are in the top right of the plot.
