Table 2.

Logistic regression analyses of predictors for the presence of minimal hepatic encephalopathy (MHE) in patients with liver cirrhosis

	Model 1a	P value	Model 2b	P value
	OR (95% CI)		OR (95% CI)
sNfL	1.077 (1.027–1.130)	0.002	1.071 (1.022–1.123)	0.004
MELD score	0.863 (0.692–1.077)	0.193	0.875 (0.706–1.084)	0.223
Albumin serum levels	0.924 (0.819–1.042)	0.196	0.920 (0.818–1.036)	0.169
History of OHE	5.235 (0.341–80.284)	0.235

CI, confidence interval; MELD, model for end-stage liver disease; OHE, overt hepatic encephalopathy; OR, odds ratio; sNfL, serum neurofilament light chains.

^aModel 1 included sNfL, MELD score, albumin serum levels, and history of OHE.

^bIn model 2, patients with a history of OHE were excluded, and the model included the variables: sNfL, MELD score, and albumin serum levels.