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. 2021 Jul 24;12(10):1640–1649. doi: 10.1039/d1md00199j

Cell-internalizing aptamers and their known uptake mechanisms described in the main text. CME: clathrin-mediated endocytosis, CvME: caveolae-mediated endocytosis.

Aptamer name Uptake mechanism Ref.
Apt-2 and Apt-10 CME 63
R13 CME and CvME 75
A10 CME 78
C10.36 CME 80
sgc8 CvME 88
AS1411 CME, macropinocytosis 67, 94