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. 2021 Oct 6;8:750558. doi: 10.3389/fmolb.2021.750558

TABLE 1.

Basic characteristics of included studies.

Author Country Design Participants male/female Age (years) BMI (kg/m2) Smoking Respiratory comorbidities Time of assessment Quality rating
Huang et al., (2020) China retrospective 57 26M/31F 46.7 ± 13.7 23.9 ± 3.5 History of smoking 9 (15.7%) No patient was reported having chronic repiratory diseases 30 days after discharge from the hospital high
Venturelli et al., (2021) Italy prospective 767 515M/252F 63 ± 13.6 NR Active smoker 33 (4.3%) History of smoking 179 (23.3%) NR 81 (66–106) days after hospital discharge high
You et al., (2020) China prospective 18 10M/8F 50.7 ± 12.1 26.4 ± 2.8 NR No patient was reported having chronic repiratory diseases 38 ± 13.4 days after hospital discharge high
Lerum et al., (2021) Norway prospective 103 54M/49F 59 (49–72) 25.8 (23.8–29.6) Current smoker 3 (3.4%) previous smoker 34 (39%) NR 3 months after hospital admission poor
Daher et al., (2020) Germany prospective 33 22M/11F 64 ± 3 28 (24–31) NR 7 (21%) 6 weeks after hospital discharge high
Wu et al., (2021) China prospective, longitudinal, cohort  83 47M/36F 60 (52–66) 25 (23.5–27.1) NR No patient was reported having chronic repiratory diseases 3 months, 6 months, 9 months, 12 months after hospital discharge high
Liang et al., (2020) China Prospective 76 21M/55F 41.3 ± 13.8 23.7 ± 4.5 NR Cough 45 (60%) Increased sputum production 33 (43%) Activity chest tightness and palpitations 47 (62%) 3 -months follow-up study after discharge high
Bellan et al., (2021) Italy prospective cohort study 238 142M/96F 61 (51–71) NR Never 139(58.4%)Former 74(31.1%)Current 25(10.5%)Pack-years,median(IQR) 15(7.25–36) No patient was reported having chronic repiratory diseases 4 months after discharge high
Li et al., (2020) China a prospective study 18 NR NR History of smoking 3(16.6%) history of tuberculosis 1 (5.5%) Near discharge and in quarantine period (2 weeks after discharge) high
van den Borst et al., (2020) Netherlands Prospective 124 74M/50F 59 ± 14 NR Never 48(39%)Former 74(60%)Current 2(2%) asthma 12 (10%) chronic lung diseases 23 (19%) other lung diseases 4 (3%) Three months after recovery high
Mo et al., (2020) China Prospective 110 55M/55F 49.1 ± 14.0 23.5 ± 3.0 History of smoking 13 (11.8%) asthma 1 (0.9%) chronic bronchitis 1 (0.9%) bronchiectasis 1 (0.9%) At time of hospital discharge poor
Zhao et al., (2020) China retrospective 55 22M/23F 47.7 ± 15.5 NR active 2 (3.6%) former 2 (3.6%) cough 7 (43.75%) 3 months after hospital discharge high
Huang et al., (2021) China prospective cohort study 1733 897M/836F 57 (47–65) NR Never-smoker 1585/1731 (92%) Current smoker 102/1731 (6%) Former smoker 44/1731 (3%) Chronic obstructive pulmonary disorder 31 (2%) 153.0 (146.0–160.0) days after hospital discharge high

NR, not reported; BMI, body mass index; M, male; F, female.