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The calculated pharmacodynamic parameters of F5, Azopt eye drops, and Cidamex tablets (mean ± SD, n = 3).
| Formulation | Max. % decrease in IOP | Tmax (h) | AUC0–10 | MRT (h) |
|---|---|---|---|---|
| F5 | 38.22 ± 0.54 | 2 ± 0 | 196.9 ± 7.88 | 4.22 ± 0.17 |
| Azopt eye drops | 31.14 ± 2.61 | 1.83 ± 0.29 | 84.06 ± 5.37 | 2.36 ± 0.22 |
| Cidamex tablets | 21.99 ± 0.99 | 1.67 ± 0.29 | 64.5 ± 13.65 | 2.62 ± 0.16 |
