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. 2021 Oct 20;41(42):8790–8800. doi: 10.1523/JNEUROSCI.1103-21.2021

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Copyright © 2021 Johnson et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Figure 4. — Photoinhibition of eNpHR-expressing VGAT neurons attenuates lordosis. Photoinhibition of eNpHR (light yellow bars) significantly reduced LQ as compared with the initial pre-test condition (p = 0.009), as well as the pre-test (p = 0.001) and photoinhibition condition (p = 0.0003) in mice that received the control virus (dark yellow bars). Two-way ANOVA followed by Tukey's multiple comparisons post hoc test indicated a significant interaction (F_(1,16) = 10.25, p = 0.006), and a main effect of viral treatment (F_(1,16) = 21.89, p = 0.0003) and photoinhibition (F_(1,16) = 4.911, p = 0.04). Values expressed as mean ± SEM; **p < 0.01, +p < 0.001, ++p < 0.0005.