Table 3.
Effect of T. catappa aqueous extract single-dose treatment on haematological parameters in acute toxicity study.
| Parameter | Control | 1000 mg/kg | 2500 mg/kg | 5000 mg/kg |
|---|---|---|---|---|
| WBC (x1012/L) | 6.01 ± 0.90 | 6.83 ± 0.65 | 6.63 ± 0.43 | 6.29 ± 0.60 |
| Lymphocytes (x109/L) | 1.84 ± 0.28 | 1.82 ± 0.47 | 1.69 ± 0.39 | 1.98 ± 0.20 |
| MID (x109/L) | 2.28 ± 0.45 | 1.80 ± 0.57 | 2.76 ± 0.98 | 2.58 ± 0.46 |
| Granulocytes (x109/L) | 3.14 ± 0.26 | 2.79 ± 1.16 | 2.96 ± 0.56 | 2.64 ± 1.05 |
| HB (g/dL) | 27.85 ± 5.85 | 28.17 ± 3.04 | 26.99 ± 2.44 | 24.76 ± 9.76 |
| RBC (x107/L) | 7.93 ± 0.98 | 7.86 ± 0.94 | 7.64 ± 0.84 | 7.46 ± 0.73 |
| HCT (%) | 54.86 ± 3.07 | 52.28 ± 8.03 | 59.48 ± 4.41 | 55.88 ± 3.11 |
| PLT (x1012/L) | 577.89 ± 25.37 | 563.62 ± 20.94 | 578.67 ± 29.01 | 567.20 ± 24.95 |
| PCT (%) | 0.62 ± 0.09 | 0.59 ± 0.06 | 0.61 ± 0.06 | 0.60 ± 0.11 |
Data are presented as mean ± SEM (n=5). Values without superscripts across a row are not significantly different at p<0.05. MID: Medium ranged monocytes, eosinophils, basophils, blasts and other precursor white cells; PCT: plateletcrit.