Table 5.
Effect of T. catappa aqueous extract 28-day repeated dose treatment on haematological parameters in sub-acute toxicity study.
| Parameter | Control | 200 mg/kg | 400 mg/kg | 800 mg/kg |
|---|---|---|---|---|
| WBC (x1012/L) | 6.11 ± 0.78 | 6.19 ± 0.36 | 6.03 ± 0.43 | 6.06 ± 0.60 |
| Lymphocytes (x109/L) | 1.04 ± 0.19 | 1.12 ± 0.53 | 1.09 ± 0.61 | 1.07 ± 0.88 |
| MID (x109/L) | 2.28 ± 0.45 | 1.80 ± 0.57 | 2.76 ± 0.98 | 2.58 ± 0.46 |
| Granulocytes (x109/L) | 1.74 ± 0.26 | 2.62 ± 1.16 | 1.46 ± 0.56 | 2.64 ± 1.05 |
| HB (g/dL) | 24.65 ± 1.43 | 23.17 ± 1.64 | 26.99 ± 2.44 | 24.76 ± 1.72 |
| RBC (x107/L) | 7.43 ± 0.87 | 7.58 ± 0.32 | 7.30 ± 0.58 | 7.45 ± 0.45 |
| HCT (%) | 44.26 ± 3.07 | 42.38 ± 8.16 | 49.68 ± 6.41 | 50.00 ± 7.11 |
| PLT (x1012/L) | 571.40 ± 45.37 | 593.62 ± 69.90 | 588.67 ± 27.45 | 607.20 ± 54.55 |
| PCT (%) | 0.61 ± 0.05 | 0.63 ± 0.07 | 0.56 ± 0.09 | 0.64 ± 0.03 |
Data are represented as mean ± SEM (n=5). Values without superscripts across a row are not significantly different at p<0.05. MID: Medium ranged monocytes, eosinophils, basophils, blasts and other precursor white cells; PCT: plateletcrit.