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. 2021 Nov;20(11):895–906. doi: 10.1016/S1474-4422(21)00263-5

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© 2021 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Participant procedures and data collection timepoints

Safety blood assessments included measures of electrolytes, creatinine, and liver function tests according to ranges for inclusion and exclusion defined in the protocol. Cognitive assessment was based on the Alzheimer's Disease Assessment Scale-cognitive subscale (participant), Neuropsychiatry Inventory (study companion), Bristol Activities of Daily Living Scale (study companion), Dementia Quality of Life (participant), and Dementia Quality of Life-Proxy (study companion). MMSE=Mini-Mental State Examination.