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. 2021 Sep 12;476(12):4507–4516. doi: 10.1007/s11010-021-04231-0

Table 3.

Effect of deuterium content of drinking water on the metabolic parameters of diabetic rats treated with insulin (twice 1 IU/300 g bw./day)

DDW Body weight Chow Water consumption Diuresis Glycosuria
(ppm) (g) (g/100 g.bw./day) (ml/100 g.bw./day) (ml/100 g.bw./day) (mmol/100 g.bw./day)
150 258.3 ± 33.3 24.2 ± 3.43 145.2 ± 18.2 83.3 ± 17.5 119.7 ± 16.8
(8)
125 350.0 ± 36.7 10.9 ± 1.4++ 42.4 ± 4.5++ 19.3 ± 2.9++ 47.1 ± 9.8++
(8)
105 323.2 ± 36.8 16.3 ± 3.4+ 82.1 ± 16.9+ 35.6 ± 20.6+ 63.7 ± 20.9+
(7)
75 315.1 ± 24.0 17.4 ± 2.4 87.8 ± 19.1 50.7 ± 16.0 88.5 ± 26.8
(8)
25 306.4 ± 34.7 19.2 ± 2.7 95.9 ± 22.4 71.0 ± 21.1 93.6 ± 16.5
(8)