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. 2021 May 17;15(11):3207–3220. doi: 10.1038/s41396-021-00998-8

Fig. 2. Altered plasma metabolome profiles in cachexia.

Fig. 2

A Principal coordinate analysis (PCoA) plot of cachexia and non-cachexia patient groups based on plasma metabolomic profiles (Bray–Curtis distance) (p = 0.026, r = 0.110, ANOSIM). B Differentially abundant metabolite classes (*p < 0.05, **p < 0.01, Wilcoxon rank-sum test). Orange: higher abundance in cachexia; green: lower abundance in cachexia group. C Plasma amino acids with significant differences between cachexia and non-cachexia patient groups (p < 0.05, Student’s t-test).