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. 2021 Oct 7;12:713717. doi: 10.3389/fphys.2021.713717

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Copyright © 2021 Kuwabara, Salavatian, Howard-Quijano, Yamaguchi, Lundquist and Mahajan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Change in activation recovery interval (ARI) during the experiments with DRG stimulation at 1 kHz. (A) Changes in ARI corrected by heart rate (cARI) during the experimental protocol. Before DRG stimulation, cARI reduced after the pacing with significant difference (*P = 0.0378 from BL1), but there was no significant difference after DRG stimulation (P = 0.2858 from BL2). BL, baseline; S1S2 Pacing, 1 min post-pacing before or after DRG stimulation; DRG30, 30 min after the initiation of DRG stimulation. (B) Reduction of cARI at 1 min post-pacing from baseline or DRG30. DRG stimulation decreased the reduction of cARI with significant difference (*P = 0.013). Data are reported as mean ± standard error (SE).