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Schematic diagram of cerebral vascular endothelial glycocalyx. Syndecan and glypican are membrane-bound proteoglycans-core skeletons, to which chondroitin sulfate and heparan sulfate are connected. Syndecans are transmembrane proteoglycans. Glypicans attach to the cell surface through glycosylphosphatidylinositol anchors. Hyaluronic acid is connected to the endothelial cell membrane through the CD44 receptor.
