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. 2021 Oct 7;15:739699. doi: 10.3389/fncel.2021.739699

FIGURE 2.

FIGURE 2

The intact glycocalyx can maintain the permeability of the blood-brain barrier. Damage to the glycocalyx will increase the permeability of the blood-brain barrier (for example, albumin exudation). The CAMs and PECAM hidden in the glycocalyx are exposed due to the shedding of the glycocalyx, causing the aggregation of leukocytes and platelets. CAMs, endothelial cell adhesion molecules. PECAM, platelet/endothelial cell adhesion molecule.