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. 2021 Oct 7;11:756205. doi: 10.3389/fonc.2021.756205

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Copyright © 2021 Li, Zhao, Zhang, Tao, Shen, Li, Ma, Li and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Tumor formations in NOD/SCID mice by PLC/PRF/5. (A) The volume and weight of the tumor formed by PLC/PRF/5 subcutaneously injected into NOD/SCID mice with or without mixed with isolated Exo (5 μg/ml) from the same cell culture medium. (B) The volume and weight of the tumor formed by PLC/PRF/5 subcutaneously injected into NOD/SCID mice mixed with Exo (5 μg/ml) isolated from culture medium of the vector or Shh shRNA containing lentivirus transfected cells. *p < 0.05, **p < 0.01.