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. 2021 Oct 7;11:756205. doi: 10.3389/fonc.2021.756205

Figure 6.

Figure 6

(A) Levels of plasma Shh and Exo-Shh isolated from plasma from healthy donors and HCC patients as determined by ELISA. (B) Levels of Exo-Shh isolated from plasma of HCC patients grouped based on tissue GLI-1 and PTCH1 levels. (C) Levels of Exo-Shh isolated from plasma of HCC patients grouped based on cancer TNM stage, tumor numbers, and histological grade. (D) Recurrence of HCC after surgical sections grouped by the Exo-Shh levels. *p < 0.05, **p < 0.01.