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. 2021 Oct 7;8:747928. doi: 10.3389/fnut.2021.747928

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Copyright © 2021 Wassie, Niu, Xie, Wang and Xin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Biological activities and health benefits of E. prolifera polysaccharides. The injection or dietary supplementation of E. prolifera polysaccharides modulate gut microbiota and stimulate short-chain fatty acid production. In addition, it stimulates antioxidant activities, alleviates inflammation, reduced serum TG, CHOL, and LDL levels, and reduces fat accumulation via a different mechanism. EPP: E. prolifera polysaccharide; NF-κB: Nuclear factor kappa-light-chain-enhancer of activated B cells; IL-2: Interleukin 2; IL-6: Interleukin; IL-10: Interleukin; NRF2: Nuclear factor erythroid 2-related factor 2; SOD: Superoxide dismutase; CAT: Catalase; GSH-Px: Glutathione peroxidase; TAC: Total antioxidant capacity; TG: Triglyceride; CHOL: Cholesterol; LDL: Low-density lipoprotein; HDL: High-density lipoprotein; CYP7A: Cholesterol 7 alpha-hydroxylase; SREBP1c: Sterol regulatory element-binding protein-1c.