Fig. 5.

Predicting diagnosis and prognostic performance in the external validation set. ROC curve (a) and HRs based on univariate (b) and multivariate (d) analyses are exhibited. KM survival curves for the external validation set (c) and some other subgroups: age > 60 (e); tumour size ≤5 (f); histologic grade 3 (g); pT stage 3 (h); pN stage 0 (i); pN stage 3 (j); pM stage 0 (k); pTNM stage 2 (l) and pTNM stage 3 (m). ***, P < 0.001; **, P < 0.01; *, P < 0.05. ROC, receiver operating characteristic; AUC, area under the curve. The P-value of Kaplan-Meier survival curve was evaluated by Log-Rank test. The P-value of HR was calculated by Cox analyse.