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. 2021 Oct 19;6(6):100286. doi: 10.1016/j.esmoop.2021.100286

Figure 2.

Figure 2

Multivariate Cox regression analyses of cardiovascular adverse event onset in the immune checkpoint inhibitor cohort, by type of cardiovascular adverse event and overall, showing hazard ratios with 95% confidence intervals.

For the bottom right panel (any CVAE analysis), only the first of any five CVAEs to occur was considered an event. Significant risk factors are highlighted in red (P < 0.05).

CI, confidence interval; CTLA-4, cytotoxic T-lymphocyte-associated protein 4; CVAE, cardiovascular adverse event; HR, hazard ratio; irAE, immune-related adverse event; PD-1, programmed cell death protein 1.