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. 2021 Oct 14;12:100139. doi: 10.1016/j.metop.2021.100139

Table 3.

Antihyperglycemic effect of the single dose of the solvent fractions on STZ-induced diabetic mice.

Group Blood glucose level (mg/dl)
0hr 2hr 4hr 6hr 8hr
DW 10 mg/kg 320.33 ± 6.94 318.00 ± 9.54 326.67 ± 5.67 327.33 ± 8.65 322.67 ± 5.94
GLC 5 mg/kg 343.83 ± 11.25 268.50 ± 16.54β3 205.00 ± 6.89β3,n3 180.33 ± 16.54β3,n3 166.00 ± 11.25β3,n3
AQF 100 mg/kg 309.67 ± 9.65 292.33 ± 10.36 282.17 ± 11.02 268.83 ± 11.25 262.67 ± 13.52
AQF 200 mg/kg 325.00 ± 15.32 280.33 ± 9.67 267.50 ± 5.67β1 254.83 ± 19.54β2,n1 238.17 ± 9.65β3,n3
AQF 400 mg/kg 298.17 ± 9.67 250.17 ± 12.54β3\1 245.50 ± 13.54β2,n1 231.17 ± 15.68β3,n3 183.00 ± 14.52β3,n3
EAF 100 mg/kg 327.67 ± 14.25 299.17 ± 8.67 281.83 ± 9.82 255.67 ± 13.24n1 247.17 ± 8.69β1,n2
EAF 200 mg/kg 325.50 ± 11.07 267.67 ± 15.64β2 255.33 ± 7.68β2,n1 247.83 ± 17.36β3,n2 242.50 ± 10.36β3,n2
EAF 400 mg/kg 314.83 ± 8.87 257.67 ± 13.54β1 245.33 ± 14.25β2,n1 236.50 ± 9.58β2,n3 224.00 ± 9.58β3,n3
CHF 100 mg/kg 307.83 ± 10.24 287.17 ± 16.54 273.50 ± 14.56 268.00 ± 15.21 262.00 ± 14.27n1
CHF 200 mg/kg 318.00 ± 9.54 286.83 ± 12.34 274.67 ± 9.87 269.67 ± 9.58 255.17 ± 11.38β1,n1
CHF 400 mg/kg 328.50 ± 7.58 286.33 ± 11.58 269.67 ± 13.24β1 260.67 ± 10.57β2,n1 254.17 ± 9.68β3,n1

Each value represents mean ± SEM; n=6 for each treatment. nCompared to the negative control, βcompared to baseline blood glucose level. 1p < 0.05, 2p <0.01, and 3p < 0.001, AQF100=aqueous fraction 100 mg/kg, AQF200=aqueous fraction 200 mg/kg, AQF400=aqueous fraction 400 mg/kg, EAF100=ethyl acetate fraction 100 mg/kg, EAF200=ethyl acetate fraction 200 mg/kg, EAF400=ethyl acetate fraction 400mg/kg, CFF100=chloroform fraction 100 mg/kg, CFF200=chloroform fraction 200 mg/kg, CFF400=chloroform fraction 400 mg/kg, DW10=Distilled water 10 ml/kg and GLC5=glibenclamide 5 mg/kg.