Table 1.
Patient cohort characteristics separated for the severity of bronchopulmonary dysplasia (BPD).
|
No/mild BPD
n = 144 |
Moderate/severe BPD
n = 63 |
p-value | |
|---|---|---|---|
| Gestational age (weeks) | 27 + 2 (25 + 6; 28 + 5) | 25 + 0 (24 + 2; 26 + 2) | <0.0001 |
| Proportion of infants <28 weeks of gestation | 94 (65.3) | 59 (93.7) | 0.005 |
| Birth weight (g) | 880 (740; 960) | 680 (530; 790) | <0.0001 |
| Proportion of infants <750 g | 42 (29.2) | 42 (66.7) | 0.323 |
| Small for gestational age | 31 (21.5) | 19 (30.2) | 0.182 |
| Male sex | 51 (35.4) | 37 (58.7) | 0.002 |
| Multiple birth | 42 (29.2) | 22 (34.9) | 0.412 |
| No antenatal steroids | 24 (16.7) | 9 (14.3) | |
| Antenatal steroids ≤ 7 days | 67 (46.5) | 37 (58.7) | |
| Antenatal steroids >7 days | 53 (36.8) | 17 (27.0) | 0.924 |
| Surfactant therapy | 81 (56.3) | 54 (85.7) | <0.0001 |
| Invasive mechanical ventilation (days) | 2 (0; 29) | 21 (0; 187) | <0.0001 |
| Ventilatory support (days) | 29 (0; 77) | 62 (13; 165) | 0.001 |
Data are presented as n (%) or median and interquartile range (Q1; Q3), if not indicated differently. p < 0.05, Mann–Whitney-U or Chi-squared test. The statistically significant results are indicated by bold print. Ventilatory support comprises the total duration of all modes of non-invasive ventilation with provision of positive end expiratory pressure of 3-cm H2O or higher.