TABLE 4.

Qualitative scoring of studies on polyherbal combinations used in animals of Metabolic Syndrome models.

	References	Dosage of herb provided	Components and rationale for dosing	animal ethical approval, Yes = 1, No = 0	Euthanasia protocol mentioned/followed, Yes = 1, No = 0	Model validated for MetS	Positive control used, Yes = 1, No = 0	Met S parameters assessed >3 = 1; <3 = 0	Effect 3/5 parameters met = good effect (score 1) <3/5 = not so good (score 0)	Total score for Quality, 8	Link
1	Thota et al. (2014)	1	1	1	1	1	0	1	1	7	https://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.637.1093&rep=rep1&type=pdf
2	Sung et al. (2014)	1	1	1	1	1	0	1	1	7	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193160/
3	Li et al. (2013)	1	1	1	0	1	1	1	1	7	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695866/
4	Kho et al. (2016)	1	1	1	0	1	1	1	1	7	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784406/pdf/12906_2016_Article_1063.pdf
5	Yao et al. (2017b)	1	1	1	1	1	0	1	1	7	https://link.springer.com/article/10.1186/s12906-017-1557-y
6	Amin et al. (2015a)	1	1	1	0	1	1	1	1	7	https://journals.lww.com/cardiovascularpharm/Abstract/2015/02000/Coadministration_of_Black_Seeds_and_Turmeric_Shows.12.aspx
7	Mounts et al. (2015)	1	1	1	1	1	0	1	1	7	https://www.researchgate.net/publication/281189904_Feeding_Soy_with_Probiotic_Attenuates_Obesity-Related_Metabolic_Syndrome_Traits_in_Obese_Zucker_Rats
8	Lee et al. (2015b)	1	1	1	0	1	0	1	1	7	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609822/
9	Hu et al. (2014)	1	1	1	0	1	1	1	1	7	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943467/
10	Gao et al. (2015)	1	1	1	1	1	1	1	0	7	https://www.hindawi.com/journals/ecam/2015/501272/
11	Kaur and C, (2012)	1	1	1	0	1	1	1	1	7	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317057/
12	Tan et al. (2013)	1	1	1	1	1	1	1	0	7	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588405/pdf/ECAM2013-306738.pdf
13	Wei et al. (2012)	1	1	1	1	1	1	0	0	6	https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0030332
14	Azushima et al. (2013)	1	1	1	1	1	0	1	0	6	https://journals.plos.org/plosone/article/comments?id=10.1371/journal.pone.0075560
15	Li et al. (2015)	1	1	1	0	1	0	1	1	6	https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0122024
16	Chen et al. (2017)	1	1	1	0	1	1	0	1	6	https://pubs.rsc.org/en/content/articlepdf/2017/ra/c7ra09779dSupplementary reference: http://www.rsc.org/suppdata/c7/ra/c7ra09779d/c7ra09779d1.pdf
17	Leong et al. (2013)	1	1	1	1	1	0	1	0	6	https://pdfs.semanticscholar.org/670a/eb206f240938b3299e6a18e2fdd97c43ae70.pdf
18	Tan et al. (2011)	1	1	1	0	1	1	0	1	6	https://www.researchgate.net/publication/47447592_Chinese_herbal_extracts_SK0506_as_a_potential_candidate_for_the_therapy_of_the_metabolic_syndrome
19	Liu and Shi, (2015)	1	0	0	0	1	1	1	1	5	https://pubmed.ncbi.nlm.nih.gov/25902033/
20	Lim et al. (2019)	1	1	1	0	1	0	0	1	5	https://www.nature.com/articles/s41598-019-45099-x
21	A. Ahmed et al. (2009)	1	1	0	1	1	0	0	1	5	http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.321.1771&rep=rep1&type=pdf
22	Jang et al. (2018)	1	0	1	0	1	0	1	0	4	https://www.hindawi.com/journals/ecam/2018/5614091/
23	Wat et al. (2018)	1	1	1	1	1	0	0	0	4	https://pubmed.ncbi.nlm.nih.gov/29655677/
24	Park et al. (2009)	0	0	0	0	1	1	0	0	2	https://www.researchgate.net/publication/288976056_Effects_of_herbal_complex_on_blood_glucose_in_streptozotocin-induced_diabetic_rats_and_in_mice_model_of_metabolic_syndrome