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. 2021 Oct 7;12:700718. doi: 10.3389/fmicb.2021.700718

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Copyright © 2021 Zhang, Li, Chen and Qin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) LEfSe analysis revealed significant changes in the fecal microbiota compositions before and after FMT. (B) Spearman correlation analysis revealed a correlation between patients’ clinical symptoms and the significantly altered bacteria from the LEfSe analysis. Fusicatenibacter, Paraprevotella, Allisonella, Coprococcus, Phascolarctobacterium, Acidaminococcaceae, Clostridiales, and class Clostridia were correlated with relief of patients’ constipation symptoms, and Lachnoanaerobaculum may be correlated with constipation severity (“*” represents 0.01 ≤ p < 0.05; “**” represents 0.001 ≤ p < 0.01).