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. 2021 Oct 7;12:700718. doi: 10.3389/fmicb.2021.700718

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Copyright © 2021 Zhang, Li, Chen and Qin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Weighed UniFrac distances of each donor-recipient pair before and after FMT. (A) Each graph shows the changes in distance between recipients and their donor. Fecal microbial profiles of most recipients of Donor 1 and all recipients of Donors 3 and 4 became more similar to those of their donor, while most recipients of Donor 2 showed minimal change or became less similar to those of their donor. (B) PCoA of the microbiota compositions based on UniFrac distances showed the overall beta diversities of the 4 donors and the pre- and post-FMT samples of the 18 patients (left) and of each donor-recipient group (right).