Table 2.
Clinicopathologic characteristics of the different sets for patients with colorectal cancer.
| Characteristics | COAD Cohort (n = 551) | READ Cohort (n = 186) | GSE39582 Cohort (n = 585) |
|---|---|---|---|
| Mean age (SD, range), years | 67 (13, 31–90) | 64 (12, 31–90) | 67 (13, 54–80) |
| Gender (male/female) (percent) | 284/262 (52/48) | 99/87 (53/47) | 323/263 (55/45) |
| Pathological stage (percent) | |||
| I | 86 (16) | 35 (19) | 37 (6) |
| II | 219 (40) | 55 (30) | 266 (46) |
| III | 152 (27) | 56 (30) | 209 (36) |
| IV | 78 (14) | 28 (15) | 60 (10) |
| NA | 16 (3) | 11 (6) | 13 (2) |
| Primary tumor location (percent) | |||
| Rectum | 0 | 186 (100) | NA |
| Left colon | 218 (40) | 0 | NA |
| Right colon | 309 (56) | 0 | NA |
| NA | 24 (4) | 0 | NA |
| Mismatch repair protein (percent) | |||
| pMMR | 343 (62) | 142 (76) | 459 (79) |
| dMMR | 66 (12) | 9 (5) | 77 (13) |
| NA | 142 (26) | 35 (19) | 49 (8) |
| Median follow-up (SD, range), months | 28 (26, 0–150) | 24 (23, 0–131) | 2 (1.3, 0–6.7) |
dMMR, mismatch repair-deficient; MMR, mismatch repair; pMMR, proficient mismatch repair.
NA, Not Available.