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. 2021 Oct 7;11:756216. doi: 10.3389/fonc.2021.756216

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Copyright © 2021 Yang, Fan, Gu, Yu, Chen, Lv, Liu, Wang and Zhang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Nomogram for the prediction of MVI presence in patients with solitary HCC. The nomogram was established based on the MR radiomics signature and 2 independent clinicopathological risk factors: peritumoral enhancement and tumour growth type (type 1: smooth regular nodule growth; type 2: focal extranodular growth; type 3: multinodular confluent growth; and type 4: infiltrative growth). Plots (B, C) present the calibration curve of the nomogram in the training and validation sets, respectively. The 45° gray line represents the ideal prediction, and the purple line represents the predictive performance of the nomogram. The purple line has a closer fit to the gray line, which indicates that the predicted MVI probability has good agreement with the actual presence of MVI.