Skip to main content
. 2021 Oct 7;15:759574. doi: 10.3389/fnbeh.2021.759574

FIGURE 1.

FIGURE 1

Baseline depression-like behaviors in P22–26 mouse cohort. (A) In the tail suspension test, C57BL/6N mice showed a significant increase in the baseline immobility duration compared to both DBA/2 and FVB/N mice. Additionally, FVB/N mice showed a significant increase in the latency to first immobility compared to both C57BL/6N and DBA/2 mice. (B) In the sucrose preference test, DBA/2 mice showed a lower sucrose preference index than both C57BL/6N and FVB/N mice. (C) In the forced swim test, FVB/N mice showed lower immobility duration and increased latency to first immobility than C57BL/6N and DBA/2 mice. C57BL/6N showed a decreased total traveled distance compared to DBA/2 and FVB/N mice. In (A–C), no sex difference was revealed within any of the aforementioned strains. Blue and red dots represent males and females, respectively. Two-way ANOVA followed by Tukey post hoc test,*p ≤ 0.05, **p ≤ 0.01, and ***p ≤ 0.001. Error bars indicate the standard error of the mean (SEM).