FIGURE 3.

Gene expression in (A) ascending colon and (B) descending colon with high CDKN2A (p16^INK4A and p14^ARF) expression, shown relative to gene expression in ascending or descending colon with low p16 expression, which has been normalized to 1 for each gene (shown by dashed line). ATP5B and GAPDH were used as endogenous controls. Results represent fold-change differences. #P < 0.1; *P < 0.05; **P < 0.01; and ***P < 0.001. Student’s t-test used to calculate P value for each gene, comparing between age groups.