Table 1.
At the time of first administration | At the time of administration after ICI failure | |||
---|---|---|---|---|
Blood chemistry | ||||
TP | 6.9 g/dL | 7.1 g/dL | ||
Alb | 4.1 g/dL | 4.1 g/dL | ||
BUN | 16 mg/dL | 15 mg/dL | ||
Cr | 0.64 mg/dL | 0.69 mg/dL | ||
T-bil | 0.4 mg/dL | 0.4 mg/dL | ||
D-bil | 0.1 mg/dL | 0.1 mg/dL | ||
ALP | 277 U/L | 251 U/L | ||
AMY | 91 U/L | 70 U/L | ||
LDH | 189 U/L | 158 U/L | ||
AST | 16 U/L | 19 U/L | ||
ALT | 16 U/L | 20 U/L | ||
γGTP | 20 U/L | 20 U/L | ||
CRP | 0.158 mg/dL | 0.024 mg/dL | ||
ALBI score | −2.93 | −2.93 | ||
ALBI grade | Grade 1 | Grade 1 | ||
| ||||
Coagulation | ||||
PT | 102.9% | 95.0% | ||
INR | 0.99 | 1.02 |
ICI, immune checkpoint inhibitors; AST, aspartate aminotransferase; ALT, alanine aminotransferase; CRP, C-reactive protein; ALBI, albumin-bilirubin; PT, prothrombin time; INR, international normalized ratio.