Skip to main content
. 2021 Jul 9;12(5):1543–1565. doi: 10.1016/j.jcmgh.2021.06.023

Figure 7.

Figure 7

Differential immune cell infiltration after chemokine injection in orthotopic murine tumors. Flow cytometric analysis, in lymphoid aggregate negative tumors from PBS-treated (n = 6) and TLS+ CXCL13/CCL21-treated (n = 6) mice, of (A) CD19+ B cells out of CD45+ cells, (B) CD3+ T cells out of CD45+ cells, (C) CD8+ cytotoxic T cells out of CD3+ T cells, (D) CD4+ helper T cells out of CD3+ T cells, (E) FOXP3+ regulatory T cells out of CD4+CD3+ T cells, (F) CD11b+ myeloid cells out of CD45+ cells, and (G) tumor weight in LA–tumors from PBS-treated (n = 6) and TLS+ CXCL13/CCL21–treated (n = 6) mice. Each data point represents 1 mouse. Two-sample Kolmogorov-Smirnov test: ∗P < .05 and ∗∗P < .01. ns, not significant.