Phylogenetic profiles of the oropharyngeal microbiome in CCs (n = 48) and Hs (n = 94). A) Average compositions and relative abundance of the bacterial community in both groups at the phylum level. B) Two phyla were remarkedly increased, while 8 phyla were remarkedly reduced in CCs versus Hs. C) Average compositions and relative abundance of the bacterial community in both groups at the genus level. D) Compared with Hs, five genera were remarkedly decreased, while five genera were remarkedly increased in CCs. E) Heatmap showed the relative abundances of differential OTUs for each sample in both groups. *
p < 0.05, **
p < 0.01, ***
p < 0.001. COVID‐19, coronavirus disease 2019; Hs, healthy controls; CCs, confirmed cases; OTUs, operational taxonomy units; centerline, median; box limits, upper and lower quartiles; circle or square symbol, mean; error bars, 95% CI.