Table 1. Characteristics of PsycheMERGE Network Sites.
| Site and group | No. of individuals genotyped (European)a | No. with WBC measurement | No. (%) genotyped and with WBC measurement | No. (%) female | No. (%) male | Mean age (SD), y | Mean (SD) length of record, y |
|---|---|---|---|---|---|---|---|
| Icahn School of Medicine at Mount Sinai | |||||||
| All | 9255 | 3668 | 823 (8.9) | 429 (52.1) | 394 (47.9) | 59.7 (16.0) | 11.2 (4.4) |
| Depression or anxiety controls | 6722 | 2499 | 578 (8.6) | 297 (51.4) | 281 (48.6) | 59.3 (16.4) | 10.7 (4.4) |
| Depression or anxiety cases | 1622 | 1169 | 245 (15.1) | 132 (53.9) | 113 (46.1) | 60.5 (15.0) | 12.5 (3.9) |
| Vanderbilt University Medical Center | |||||||
| All | 72 828 | 948 590 | 70 921 (97.4) | 39 661 (55.9) | 31 260 (44.1) | 48.1 (22.3) | 8.7 (6.3) |
| Depression or anxiety controls | 59 520 | 301 982 | 43 129 (72.5) | 22 675 (52.6) | 20 454 (47.4) | 46.8 (23.7) | 7.6 (6.1) |
| Depression or anxiety cases | 15 985 | 71 692 | 13 371 (83.6) | 8614 (64.4) | 4757 (35.6) | 50.9 (18.8) | 11.3 (6.1) |
| Million Veteran Program | |||||||
| All | 289 880 | 289 880 | 289 880 (100) | 20 871 (7.2) | 269 009 (92.8) | 64.3 (12.0) | 12.0 |
| Depression or anxiety controls | 150 328 | 150 328 | 150 328 (100) | 6163 (4.1) | 144 165 (95.9) | 67.7 (11.2) | 11.2 |
| Depression or anxiety cases | 129 552 | 129 552 | 129 552 (100) | 14 121 (10.9) | 115 431 (89.1) | 61.6 (11.9) | 12.9 |
| Mass General Brigham | |||||||
| All | 25 331 | 72 329 | 20 828 (82.2) | 10 726 (51.5) | 10 102 (48.5) | 56.1 (16.7) | 13.8 (8.3) |
| Depression or anxiety controls | 17 879 | 51 612 | 17 098 (95.6) | 8891 (52.0) | 8207 (48.0) | 59.8 (16.7) | 11.3 (7.1) |
| Depression or anxiety cases | 7452 | 20 717 | 3730 (50.1) | 2390 (64.2) | 1340 (35.9) | 56.7 (16.9) | 14.0 (6.7) |
Abbreviations: NA, not applicable; WBC, white blood cell.
a
The focused WBC analyses included only European samples, because there were no significant findings in the African ancestry LabWAS.