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. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: J Neurochem. 2021 May 21;158(2):554–568. doi: 10.1111/jnc.15371

Figure 5: Receiver operating characteristic (ROC) curves for distinguishing synucleinopathy patients (N=92) from controls (N=24) by CSF levels of (A) DOPA, (B) DA, (C) DOPAC, (D) HVA, (E) NE, (F) DHPG, and (G) MHPG.

Figure 5:

Abbreviations: DA=dopamine; DHPG=3,4-dihydroxyphenylglycol; DOPA=3,4-dihydroxyphenylalanine; DOPAC=3,4-dihydroxyphenylacetic acid; HVA=homovanillic acid; MHPG=3-methoxy-4-hydroxyphenylglycol; NE=norepinephrine. Red line indicates predictions from the null hypothesis of no distinction between the groups. Blue dashed line shows that for CSF MHPG sensitivity is 65% and specificity 80%.